eTable 3.

Association of individual items of the perceived stress scale and other covariates with mild cognitive impairment (outcome) estimated by multivariable logistic regression

		In the past 30 days, how often…
		have you felt that you were unable to control the important things in your life?		have you found that you could not cope with all the things that you had to do?
Characteristic	Category	OR	95%CI	OR	95%CI
Perceived stress	Never	1.00		1.00
	Almost never	0.96	[0.79,1.17]	1.02	[0.87,1.20]
	Sometimes	1.24*	[1.02,1.51]	1.39***	[1.17,1.65]
	Fairly often	2.15***	[1.67,2.78]	2.56***	[1.99,3.29]
	Very often	3.66***	[2.58,5.20]	3.85***	[2.74,5.42]
Sex	Female	1.00		1.00
	Male	0.97	[0.86,1.09]	0.97	[0.86,1.10]
Age (years)		1.02***	[1.01,1.02]	1.01***	[1.01,1.02]
Education (years)		0.98**	[0.96,0.99]	0.98*	[0.96,1.00]
Wealth	Poorest	1.00		1.00
	Poorer	0.97	[0.82,1.15]	0.97	[0.82,1.16]
	Middle	1.05	[0.86,1.27]	1.04	[0.86,1.26]
	Richer	0.73***	[0.61,0.88]	0.74**	[0.61,0.89]
	Richest	0.45***	[0.37,0.56]	0.46***	[0.37,0.57]
Depression	Yes vs. No	0.88	[0.65,1.17]	0.86	[0.65,1.15]
No. of chronic conditions	Per unit increase	1.19***	[1.14,1.23]	1.19***	[1.14,1.23]

Abbreviation: OR Odds ratio; CI Confidence interval

Models are mutually adjusted for all variables in the Table and country.

^*p<0.05

^**p<0.01

^***p<0.001