. Author manuscript; available in PMC: 2019 Mar 10.

Published in final edited form as: Br J Nutr. 2017 May;117(10):1403–1413. doi: 10.1017/S000711451700143X

Table 3.

Measures of ex vivo cholesterol efflux following supplementation with 50g/d isoflavone-containing soya protein compared with the control^† (Mean values with their standard errors; n 20)

	Baseline		0g/d soya protein (control)		50 g/d soya protein^‡		P _{for treatment effect}
	Mean	SEM	Mean	SEM	Mean	SEM	P _{for treatment effect}

ABCA1 (% efflux/4 h)	3.46	0.34	3.02^*	0.18	3.15	0.18	0.39
Global efflux (+cAMP) (% efflux/4 h)	9.47	0.47	8.92	0.27	9.06	0.28	0.57
Global efflux (−cAMP) (% efflux/4 h)	6.00	0.26	5.89	0.18	5.91	0.18	0.93

ABCA1, ATP-binding cassette transporter 1; cAMP, cyclic AMP; CRP, C-reactive protein.

Significant change from baseline:

P = 0.02.

^†

ABCA1-specific efflux was calculated as the difference between cAMP-stimulated and non-stimulated (−cAMP) efflux. Values were compared using the MIXED procedure (SAS version 9.4; SAS Institute Inc.). Period effects were universally non-significant (P> 0.05).

^‡

Data represent eighteen participants; two were excluded from analyses for this treatment period due to acutely elevated CRP concentrations (i.e. CRP ≥10.5 mg/l).