Table 5.
Blood markers of CVD risk following each 6-week treatment period* (Mean values with their standard errors; n 20)
| Soya protein |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline |
0 g/d (control) |
25 g/d |
50 g/d† |
P |
||||||
| Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | For treatment effect | For period effect | |
| Glucose (mmol/l) | 4.9 | 0.1 | 5.0 | 0.1 | 5.1 | 0.1 | 5.1 | 0.1 | 0.14 | 0.15 |
| log Insulin (μIU/I) | 0.70 | 0.04 | 0.73 | 0.04 | 0.69 | 0.04 | 0.73 | 0.04 | 0.74 | 0.43 |
| TC (mmol/l) | 5.1 | 0.2 | 4.9 | 0.1 | 5.0 | 0.1 | 4.9 | 0.1 | 0.64 | 0.06 |
| HDL-cholesterol (mmol/l) | 1.4 | 0.1 | 1.4 | 0.04 | 1.4 | 0.04 | 1.4 | 0.4 | 0.26 | 0.25 |
| TC:HDL-cholesterol | 3.8 | 0.2 | 3.8 | 0.1 | 3.7 | 0.1 | 3.7 | 0.1 | 0.57 | 0.87 |
| LDL-cholesterol (mmol/l) | 3.1 | 0.1 | 3.0 | 0.1 | 3.0 | 0.1 | 2.9 | 0.1 | 0.85 | 0.40 |
| log TAG (mmol/l) | 2.0 | 0.04 | 2.0 | 0.03 | 2.0 | 0.03 | 2.0 | 0.03 | 0.75 | 0.003a |
| Non-HDL-cholesterol (mmol/l) | 3.7 | 0.2 | 3.5 | 0.1 | 3.6 | 0.1 | 3.6 | 0.1 | 0.67 | 0.02b |
| log CRP (mg/l) | 0.16 | 0.10 | 0.11 | 0.07 | 0.18 | 0.07 | 0.11 | 0.07 | 0.36 | 0.02c |
TC, total cholesterol; CRP, C-reactive protein.
Period 1 values significantly lower than period 3 values in post hoc comparisons (Tukey-adjusted P = 0.002);
period 1 values significantly lower than period 3 values in post hoc comparisons (Tukey-adjusted P = 0.02);
period 1 values significantly higher than period 2 and period 3 values in post hoc comparisons (Tukey-adjusted P = 0.03 and 0.05, respectively).
Values were compared using the MIXED procedure (SAS version 9.4; SAS Institute Inc.).
Data represent eighteen participants; two were excluded from analyses for this treatment period due to acutely elevated CRP concentrations (i.e. CRP ≥10.5 mg/l).