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. 2019 Mar 4;7:38. doi: 10.3389/fpubh.2019.00038

Table 1.

Clinical information on the nine patients from whom archaea were detected in sinusitis pus.

Case Clinical information Microbiology
Bacteria Methanogens
Species Species Sequence similarity FISH Culture
Sex Age (years) Underlying condition Atopy Localization Treatment Specimen number 16S rRNA mcrA
1 Female 62 None N Left maxillary Ceftazidine + Netilmycin
Ofloxacin + rifampin
1 Corynebacterium accolens
Staphylococcus aureus
Raoultella ornithinolytica
Streptococcus pseudointermedius
Pseudomonas aeruginosa
M. oralis 99% 100% Positive Positive
2 Male 64 Undifferentiated carcinoma nasopharyngeal type, cavum N Right maxillary Amoxicillin- clavulanate 2 S. aureusStaphylococcus epidermidisP. aeruginosaPropionibacterium acnes M. smithii 99% 99% Negative Negative
3 Female 56 None N Frontal, ethmoidal, and maxillary Amoxicillin-clavulanate + ciprofloxacin 3.1 S. aureus M. smithii 99% 99% Negative Negative
3.2 S. aureus M. smithii 100% 100% Negative Negative
3.3 S. aureus M. smithii 100% 100% Negative Negative
4 Female 64 Maxillary papilloma N Right maxillary NA 4 Klebsiella oxytoca M. smithii 100% 99% Negative Negative
5 Male 20 None N Right frontal ethmoidal maxillary Amoxicillin- clavulanate +
ciprofloxacin
5 Sterile M. massiliense 100% Negative Negative Negative
6 Female 44 Asthma Y Left maxillary
Right maxillary
Cotrimoxazole 6.1 S. epidermidis
Corynebacterium propinquum
Corynebacterium avidum
M. oralis 100% 99% Positive Negative
6.2 S. epidermidis
C. propinquum
M. oralis 100% 99% Negative Negative
7 Male 64 -MALT lymphoma -Sinusal aspergilloma N Left frontal ethmoidal NA 7 P. aeruginosa
S. epidermidis
P. acnes
M. oralis 99% 100% Negative Negative
8 Female 71 Undifferentiated carcinoma nasopharyngeal type, cavum N Right maxillary Amoxicillin- clavulanate 8 S. epidermidis
P. acnes
M. oralis 100% 100% Positive Negative
9 Female 53 Nasal and sinusal polyposis Y Bilateral maxillary Amoxicillin- clavulanate 9 Propionibacterium granulorum
S. aureus
Haemophilus influenzae
M. smithii 100% NA Positive Negative

The detail on microorganisms detected in each patient is also provided. “N” stands for absence, “Y” for presence. NA, not available.