Table 3.
Logistic regression analysis of the association of DPP4 activity, BDNF, DBR, and MCI.
| Q1 | Q2 | Q3 | Q4 | |
|---|---|---|---|---|
| DPP4 activity (nmol/ml/min) | <11.97 | 11.97-16.87 | 16.88-24.02 | >24.02 |
| MCI | 21 (7.9%) | 40 (15.0%) | 39 (14.6%) | 69 (25.9%) |
| Model 1 | 1 | 2.06 (1.18, 3.59) 0.011 | 2.00 (1.14, 3.50) 0.016 | 4.09 (2.42, 6.90) < 0.001 |
| Model 2 | 1 | 1.88 (1.06, 3.33) 0.030 | 2.00 (1.12, 3.56) 0.018 | 3.78 (2.20, 6.49) < 0.001 |
| BDNF (ng/ml) | <1.71 | 1.71-2.37 | 2.38-3.22 | >3.22 |
| MCI | 70 (26.2%) | 50 (18.7%) | 26 (9.8%) | 23 (8.6%) |
| Model 1 | 1 | 0.65 (0.43, 0.98) 0.039 | 0.31 (0.19, 0.50) < 0.001 | 0.27 (0.16, 0.44) < 0.001 |
| Model 2 | 1 | 0.69 (0.45, 1.06) 0.091 | 0.31 (0.19, 0.51) < 0.001 | 0.28 (0.17, 0.48) < 0.001 |
| DBR | <4.01 | 4.01-6.86 | 6.87-12.28 | >12.28 |
| MCI | 21 (7.9%) | 31 (11.7%) | 39 (14.6%) | 78 (29.3%) |
| Model 1 | 1 | 1.55 (0.86, 2.77) 0.143 | 2.00 (1.14, 3.51) 0.015 | 4.86 (2.90, 8.16) < 0.001 |
| Model 2 | 1 | 1.52 (0.84, 2.74) 0.165 | 1.94 (1.10, 3.43) 0.023 | 4.63 (2.73, 7.88) < 0.001 |
Model 1, crude model; Model 2, Model 1 + age + gender + BMI + current smoking + habitual alcohol consumption + leisure-time physical activity + education level + annual income + statin use + NSAID use + cardiovascular disease + SBP + TG + HDL-C.