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. 2019 Mar 4;10:120. doi: 10.3389/fgene.2019.00120

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Copyright © 2019 Liu, Lu, Li and Zuo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Oct4 combination intensity and time on gene expression at different stages of cell development for 27 genes. X-axis represents different stages of cell development after 0, 1, 3, 5, 7, 11, 15, and 18 day(s). Y-axis represents parameter value. Curves in red, green, blue, and black represent values of parameters β₁, β₂, β₃ and ε from the proposed generalized linear regression model, respectively.