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Erythropoietin (Epo) in wild-type (WT) and interleukin-6 deficient (Il6KO) juvenile mice with and without CKD. (a) Serum Epo at 2 different time points: 6 and 8 weeks of adenine diet exposure. (b) Kidney and (c) liver Epo protein expression. In the liver, Epo protein expression was not different among the 4 groups of mice. Serum and tissue Epo was measured by enzyme-linked immunosorbent assay. n ≥ 5 per group. Error bars are SDs. *P < 0.05; **P < 0.01; ***P < 0.001.
