Table 2.
The angiotensin I-converting enzyme (ACE) inhibitory activity (IC50) of chemically synthesized peptides
Source fraction | Peptide | IC50 (mM) |
---|---|---|
V-m1 | Tyr-Gly | 12.68 |
Tyr-Tyr | 8.60 | |
V-m2 | Tyr-Phe-Asn-Glu | 7.62 |
V-15 | Val-Ser-Val | 9.08 |
Leu-Trp-Gly | 24.61 | |
Phe-Gly-Tyr | 2.69 | |
Val-Ser-Ser-Val | 8.49 | |
Leu-Ser-Trp | 0.89 | |
Met-Ala-Asp-Ala | 5.92 | |
Tyr-Arg-Gln | 3.09 | |
Gln-Pro-Ser-Gly-Ser-Gln | 8.78 | |
Leu-Trp-His- His-Thr | 5.21 |
IC50 value was defined as the concentration of inhibitor required to inhibit 50% of the ACE activity.