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. 2019 Feb 22;11(2):96. doi: 10.3390/pharmaceutics11020096

Table 1.

Singular change to cation chain length leading to altered physicochemical profile. IL—ionic liquid.

Chain Length Alteration Change on Physio-Chemical Properties of ILs Reference
Increase Increased viscosity [6,30]
Increase enthalpy of vaporization [6]
Increased aggregation (not necessarily ordered) [6,30,31]
Increased toxicity (bacterial and marine ecosystems) [3,32]
Increased surfactant activity [6]
Chain lengths similar to biological membranes Increased bioaccumulation (potential for toxicity) [3,20]
Decrease Increased conductance [6]
Increase in electrostatic forces [6,30]
Ordered aggregation; depends largely on polarity and geometric packing [6,31]
Increased lipase catalytic activity [19,33]
Increased polarity [6]