Figure 3.

Mx1-9R inhibited influenza virus replication in infected cells. Mx1-9R was introduced into the MDCK cells (A) 12 h prior to or (C) 3 h post PR8 infection. Viral titers in the culture supernatant were determined by plaque assay, and relative levels of vRNA were analyzed by RT-qPCR (n = 3). Data are presented as the means ± SEM. (B) Recombinant 9 arginine conjugated ovalbumin (OVA-9R) was introduced into the MDCK cells 12 h prior to PR8 infection. Then, cells were infected with 0.01 MOI of PR8 for 24 h, and relative levels of vRNA were analyzed by RT-qPCR (n = 3). Data are presented as the means ± SEM.