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. 2019 Feb 1;11(2):134. doi: 10.3390/v11020134

Table 1.

Foamy virus conference history.

Year Location Key Findings Reported
1994 London, UK
  • Identification of “human foamy virus (HFV)” being the result of a zoonotic transmission of a chimpanzee FV

  • Involvement of a defective HFV genome in viral latency

  • Details of Tas-dependent HFV transcriptional control involving internal and LTR promoter

1997 Herzogenhorn, Germany
  • Full-length sequence of a feline FV isolate

  • Reverse transcription during virus morphogenesis results in infectious FVs with a DNA genome

  • First generation replication-deficient PFV vectors

1999 Gif-sur-Yvette, France
  • Characterization of an equine FV isolate

  • FV glycoprotein-mediated subviral particle formation

  • FV glycoprotein leader peptide-dependent viral particle release mechanism

2002 Atlanta, GA, USA
  • Application of 2nd generation replication-deficient PFV vector for hematopoietic stem cell gene transfer

  • Viral genome-dependent FV Pol encapsidation mechanism

2004 Würzburg, Germany
  • Identification of FV Bet as inhibitor of the APOBEC restriction factors

  • ESCRT-complex-dependent FV release

  • First generation replication-deficient feline FV vector systems

2006 Seattle, WA, USA
  • Successful treatment of canine leukocyte adhesion deficiency by FV vector-mediated HSC gene transfer

  • Centrosomal latency of incoming FV capsids in resting cells

  • Identification of in vivo sites of FV replication in infected primates

2008 Heidelberg, Germany
  • CRM1-mediated nuclear export of unspliced FV RNAs

  • PFV protease structure

2010 Argos, Greece
  • Host cells DDX6 protein involvement in PFV genome encapsidation

  • Heparan sulfate as FV Env-dependent attachment factor

2012 Bethesda, MD, USA
  • Structure of the PFV Gag N-terminus in complex with FV Env LP peptides

  • Innate sensing of FV by plasmacytoid dendritic cells

  • Pseudotyping of FV vectors by heterologous viral glycoproteins

2014 Puławy, Poland
  • Discovery of BFV LTR encoded microRNAs

  • Host cell Polo-like kinase interaction with PFV Gag involved in proviral integration

  • Update of FV taxonomy and new nomenclature proposed

2016 Paris, France
  • Structure of the central domain of PFV Gag

  • Genetic diversity of the env gene in zoonotic gorilla and chimpanzee FV strains

2018 Dresden, Germany
  • Identification of ISG PHF11 as cellular restriction factor of FVs

  • Cross species dynamics of feline FV

  • A FV vector system for transient expression of CRISPR/Cas genome engineering tools