Table 1.
Composition of various solidified SuSMED (S-SuSMED) granules and their reconstitution properties.
| Granules | G1 | G2 | G3 | G4 | G5 | G6 |
|---|---|---|---|---|---|---|
| Composition (mg) | ||||||
| SuSMED a | 190 | 190 | 190 | 190 | 190 | 190 |
| HPC | 19 | 57 | 95 | 133 | 171 | 209 |
| FLO | 247 | 209 | 171 | 133 | 95 | 57 |
| Total | 456 | 456 | 456 | 456 | 456 | 456 |
| Reconstitution properties b | ||||||
| Droplet size (nm) | 151.2 ± 22.3 | 146.6 ± 18.1 | 140.1 ± 13.8 | 137.5 ± 15.3 | 136.0 ± 11.4 | 139.2 ± 14.2 |
| PDI | 0.34 ± 0.06 | 0.32 ± 0.07 | 0.23 ± 0.04 | 0.24 ± 0.05 | 0.24 ± 0.02 | 0.27 ± 0.03 |
a SuSMED was composed of VST (80 mg), Capmul MCM (10 mg), Tween 80 (30 mg), GEL (60 mg), and Poloxamer 407 (POL) (10 mg). b Values are presented as the mean ± SD (n = 10).