Table 2.
Composition of the S-SuSMED tablets and their characteristics.
| Tablets | S-SuSMED-T1 | S-SuSMED-T2 |
|---|---|---|
| Composition (mg) | ||
| SuSMED a | 190 | 190 |
| HPC | 57 | 133 |
| FLO | 209 | 133 |
| Kollidon® 30 | 54.9 | 54.9 |
| Primellose® | 27.5 | 27.5 |
| Magnesium stearate | 11 | 11 |
| Total | 549.4 | 549.4 |
| Characteristics b | ||
| Weight variation (mg) | 549.1 ± 1.0 | 549.2 ± 1.0 |
| Diameter (mm) | 12.01 ± 0.01 | 12.03 ± 0.02 |
| Thickness (mm) | 4.83 ± 0.03 | 4.31 ± 0.02 |
| Hardness (kP) | 8.7 ± 0.1 | 8.6 ± 0.2 |
| Friability (%) | 0.1 | 0.6 |
| Drug content (%) | 97.1 ± 2.3 | 97.7 ± 1.9 |
a SuSMED was composed of VST (80 mg), Capmul® MCM (10 mg), Tween® 80 (30 mg), GEL (60 mg), and POL (10 mg). b Values are presented as the mean ± SD (n = 10).