Figure 6.

The ROS scavenger NAC reduces ROS levels, increases the MMP, and inhibits apoptosis. (A) Changes in cell viability following DEF pretreatment with 5 or 10 mM NAC for 2 h and detected by MTT assay at 36 h. (B) Pretreatment with 5 or 10 mM NAC decreased ROS in DPV-infected cells; uninfected cells were used as a control. (C) NAC (5 or 10 mM) increased the MMP in DPV-infected cells; uninfected cells were used as a control. (D) NAC (5 or 10 mM) promoted viral replication. (E) NAC (10 mM) inhibited apoptosis induced by DPV. The data are presented as the means ± SD of three independent experiments. * p < 0.05 and ** p < 0.01, compared with the control group.