Table 2.
Group II. Patients with serological suspicion of ZIKV infection.
| Group | ID/Sample Number | Country of Infection | DPSO | PRNT (ZIKV) | ZIKV RT-PCR | ZIKV IgM Ratio (ELISA) | ZIKV IgG Ratio (ELISA) | ZIKV RAI (Last Dilution) | IgA Ratio (ELISA) | DENV IgM * | DENV IgG * |
|---|---|---|---|---|---|---|---|---|---|---|---|
| II | P30/S1 | Dominican Republic | 4 | ND | ND | Neg | Neg | Neg | Neg | Neg | |
| II | P30/S2 | 32 | ND | ND | Neg | Pos (2.9) | L (30.4) | Neg | Neg | Neg | |
| II | P31/S1 | Brazil | ≤7 | ND | ND | Equiv (1.1) | Neg | Pos (1.2) | Neg | Pos | |
| II | P31/S2 | ≤18 | Pos | ND | Pos (4.6) | Pos (3.1) | L (16.1) | Pos (5.1) | ND | Pos | |
| II | P32/S1 | Venezuela | 2 | ND | ND | Neg | Neg | Neg | Neg | Pos | |
| II | P32/S2 | 19 | Pos | ND | Pos (1.3) | Pos (6.1) | H (65.8) | Pos (5.0) | Neg | Pos | |
| II | P33/S1 | Unk | 9 | ND | Neg (b) | Pos (2.57) | Neg | Pos (4.1) | Neg * | Neg * | |
| II | P33/S2 | 30 | ND | ND | Equiv (1.0) | Pos (2.9) | L (32.4) | Neg | Neg * | Neg * | |
| II | P34/S1 | Venezuela | 49 | Pos | ND | Neg | Pos (2.9) | L (30.2) | Neg | Pos | Pos |
| II | P34/S2 | 76 | Pos | ND | Neg | Pos (3.6) | Equiv (44.9) | Neg | Neg | Pos | |
| II | P35/S1 | Colombia | unk | Pos | Neg (s) | Pos (7.4) | Pos (3.7) | L (23.4) | Pos (4.1) | Pos | Pos |
| II | P36/S1 | Brazil | 10 | ND | Neg (b,u) | Pos (2.5) | Pos (1.4) | L (31.6) | Pos (5.2) | Pos | Pos |
| II | P37/S1 | Brazil | 13 | ND | Neg (b) | Pos (4.2) | Neg | Pos (1.3) | Neg * | Pos * | |
| II | P38/S1 | Brazil | 13 | ND | Neg (b) | Pos (2.8) | Pos (1.9) | L (18.2) | Pos (5.1) | Neg * | Pos * |
| II | P38/S2 | 15 | ND | ND | Pos (1.6) | Pos (3.0) | L (29.4) | Pos (2.47) | Neg * | Pos * | |
| II | P39/S1 | Dominican Republic | 17 | ND | Neg (s) | Pos (2.4) | Pos (3.8) | L (38.1) | Pos (4.55) | ND | Pos * |
| II | P39/S2 | 45 | Pos | Neg | Pos (2.5) | Pos (2.8) | Equiv (45.5) | Equiv (0.97) | ND | Pos | |
| II | P40/S1 | Dominican Republic | unk | ND | ND | Equiv (1.0) | Pos (6.4) | Inc (72.5) | Pos (1.96) | ND | Pos |
| II | P40/S2 | 67¨ | ND | Neg (s) | Neg | Pos (6.1) | H (68.6) | Neg | ND | Pos |
DPSO—Days post illness onset; Equiv—Equivocal; Inc—inconclusive; L—low avidity; ND—not determined; Neg—negative result; Pos—positive result; PRNT—plaque reduction neutralization test; RAI—Relative avidity index; unk—unknown. (b)—blood sample; (s)—serum sample; (u)—urine sample. DENV IgM and IgG: the samples marked * were tested by IIF, the remaining by ELISA.