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. 2019 Feb 20;10(2):166. doi: 10.3390/genes10020166

Table 4.

Associations between mortality and zygosity in individual twins, birth cohorts 1961–1990, surviving to age 6; among individual twins at ages up to 50 years, and from 50 years.

All Ages,
n = 39,504
Ages ≤50,
n = 39,504
Ages >50,
n = 8711
Both sexes a HR (95%-CI) HR (95%-CI) HR (95%-CI)
Zygosity
  MZ Ref. Ref. Ref.
  SSDZ 1.07 (0.89, 1.13) 1.10 (0.91, 1.34) 0.80 (0.46, 1.40)
  OSDZ 1.21 (1.01, 1.45) * 1.23 (1.02, 1.48) * 1.05 (0.61, 1.79)
  UZ 1.83 (1.47, 2.28) *** 1.89 (1.51, 2.37) *** 1.25 (0.49, 3.20)
Males
Zygosity
  MZ Ref. Ref. Ref.
  SSDZ 1.01 (0.80, 1.28) 1.06 (0.83, 1.35) 0.63 (0.29, 1.37)
  OSDZ 1.22 (0.97, 1.53) 1.23 (0.97, 1.55) 1.14 (0.56, 2.29)
  UZ 1.86 (1.43, 2.42) *** 1.92 (1.46, 2.51) *** 1.26 (0.39, 4.11)
Females
Zygosity
  MZ Ref. Ref. Ref.
  SSDZ 1.17 (0.88, 1.56) 1.19 (0.88, 1.62) 1.04 (0.46, 2.31)
  OSDZ 1.19 (0.90, 1.58) 1.23 (0.91, 1.67) 1.14 (0.56, 2.28)
  UZ 1.71 (1.13, 2.60) * 1.78 (1.15, 2.75) ** 1.18 (0.26, 5.45)

a Baseline hazard stratified on sex. * p < 0.05, ** p < 0.01, *** p < 0.001.