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. 2019 Feb 23;11(2):132. doi: 10.3390/toxins11020132

Figure 1.

Figure 1

Effects of individual and mixtures of aflatoxin M1 (AFM1) and ochratoxin A (OTA) on cell viability of Caco-2/HT29-MTX (A) 100/0, (B) 90/10, (C) 75/25, and (D) 0/100 co-cultures. Differentiated Caco-2/HT29-MTX cells were exposed to AFM1 (0.05, 4 μg/mL), OTA (0.05, 4 μg/mL), or OTA+AFM1 (0.05, 4 μg/mL) for 48 h, then cell viability was determined by using the enhanced Cell Counting Kit-8 (CCK-8). Results are expressed as percentage of control and are means ±SEM (n = 3), respectively. Different letters (a–e) indicate significant differences in cell viability (p < 0.05). M0.05 represents AFM1 at 0.05 μg/mL, M4 represents AFM1 at 4 μg/mL, O0.05 represents OTA at 0.05 μg/mL, O4 represents OTA at 4 μg/mL, M+O0.05 represents AFM1+OTA at 0.05 μg/mL, M+O4 represents AFM1+OTA at 4 μg/ mL.