Table 1.
Cell lines and primary cultures used for frog virus 3 (FV3) infection.
| Name | Cell Culture Type | Species | Developmental Stage | Cell Morphology | FV3 Isolate for Infection |
|---|---|---|---|---|---|
| BufoTad | Cell line | American toad (Anaxyrus americanus) | Tadpole (Gosner stage 35-38) | Endothelial-like | EPC-derived isolate |
| BullTad-leg | Cell line | Bullfrog (Lithobates catesbeianus) | Tadpole (Gosner stage 40-41) | Fibroblastic | EPC-derived isolate |
| GreenTad-HF2 | Cell line | Green frog (Lithobates clamitans) | Tadpole (Gosner stage 25-27) | Fibroblastic | EPC-derived isolate |
| WoodTad-rpe | Cell line | Wood frog (Lithobates sylvaticus) | Tadpole (Gosner stage 43-45) | Epithelial | EPC-derived isolate |
| Bone marrow rXlCSF-1-derived macrophages (Mϕs) | Primary culture | African clawed frog (Xenopus laevis) | Adult | Macrophage | Baby hamster kidney (BHK-21)-derived isolate |
| Bone marrow rXlIL-34-derived Mϕs | Primary culture | African clawed frog (Xenopus laevis) | Adult | Macrophage | BHK-21-derived isolate |
| Class A scavenger receptor (SR-A)-null variant A549 cell line with an inducible human SR-AI | Cell line | Human (homo sapiens) | n/a | Epithelial | EPC-derived isolate |
n/a: non-applicable.