Table 1.

The top-ten most popular genes.

Symbol	Gene ID	Function
TP53	7157	Associated with the tumor suppressor protein p53. Mutation causes more than half of human cancers.
TNF	7124	An immune molecule associated with tumor necrosis factor, as a major drug target in inflammatory diseases.
EGFR	1956	Associated with the epidermal growth factor receptor, a membrane-bound receptor protein. Mutations may lead to drug-resistant cancer.
VEGFA	7422	Associated with vascular endothelial growth factor A, helping promote the growth of blood vessels.
APOE	348	Associated with cholesterol and lipoprotein metabolism, namely apolipoprotein E.
IL6	3569	Associated with an immune molecule namely interleukin 6, helps to stimulate and suppress inflammation.
TGFB1	7045	Associated with transforming growth factor β 1, used to regulate cell proliferation and differentiation.
MTHFR	4524	Associated with process amino acids, an enzyme named methylene-tetrahydrofolate reductase.
ESR1	2099	Associated with a nuclear receptor protein, estrogen receptor 1, which plays an important role in breast, ovarian, and endometrial cancers.
AKT1	207	Associated with a signaling protein namely kinase, helping activate other proteins by phosphorylation.