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Effects of Hepes buffer (HB), the unstructured surfactant formulation (TG), the unstructured surfactant formulation with the same Ibuprofen (IBU) concentration (TG-Ibu), and TW20-Gly loaded with IBU (NioIbu) on zymosan-induced hyperalgesia. * is for P < 0.05 and ** is for P < 0.01 versus TG. N = 10.
