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. 2019 Feb 15;11(2):81. doi: 10.3390/pharmaceutics11020081

Figure 3.

Figure 3

Non-invasive fluorescence imaging and photodynamic therapy (PDT) with PpIX-pH-PMs in live SCC7 tumor-bearing mice. In vivo time-dependent whole body imaging after injection (a); in vivo quantification of tumor target specificity of free PpIX and PpIX-pH-PMs (b); ex vivo images of organs (liver, lung, spleen, kidney, heart) and tumors (c). (d) H&E staining of tumor tissues 10 days after treatment. (e) Tumor growth of SCC7 tumor-bearing mice treated with drug injection and irradiation. Results represent means ± SDs. (n = 2). Reproduced from Reference [37] with permission from the Royal Society of Chemistry, 2010.