Table 1.
Haematological parameters of study participants.
| Parameters | Genotype of Subject | |||||
|---|---|---|---|---|---|---|
| HbAA (n = 50) | HbSC Steady State (n = 30) | HbSC VOC (n = 11) | HbSS Steady State (n = 34) | HbSS VOC (n = 15) | p-Value | |
| Hb | 11.52 ± 1.50 | 11.30 ± 1.45 | 8.22 ± 0.77 | 8.94 ± 1.10 | 6.92 ± 0.63 | <0.001 * |
| WBC | 8.76 ± 3.39 | 6.45 ± 2.41 | 10.80 ± 5.46 | 9.36 ± 3.27 | 11.79 ± 5.01 | <0.001 * |
| RBC | 4.37 ± 0.57 | 4.47 ± 0.75 | 3.37 ± 0.60 | 3.32 ± 0.63 | 2.60 ± 0.47 | <0.001 * |
| HCT | 36.00 ± 4.49 | 36.11 ± 5.04 | 26.63 ± 2.41 | 28.25 ± 3.60 | 21.48 ± 2.27 | <0.001 * |
| MCV | 82.85 ± 6.89 | 81.27 ± 6.75 | 80.55 ± 10.71 | 86.11 ± 9.07 | 83.93 ± 10.59 | 0.1280 |
| MCH | 26.62 ± 2.50 | 25.52 ± 2.43 | 25.01 ± 4.27 | 27.56 ± 3.60 | 27.17 ± 4.29 | 0.0470 * |
| MCHC | 32.00 ± 0.93 | 31.34 ± 0.91 | 30.88 ± 1.55 | 31.87 ± 1.06 | 32.24 ± 1.33 | 0.0020 * |
| RDW | 14.94 ± 1.34 | 14.05 ± 1.42 | 15.18 ± 1.64 | 15.63 ± 1.84 | 17.90 ± 2.40 | <0.001 * |
| PLT | 296.29 ± 123.87 | 261.00 ± 91.56 | 384.18 ± 183.20 | 382.41 ± 100.80 | 464.60 ± 148.78 | <0.001 * |
| MPV | 7.87 ± 0.73 | 7.84 ± 0.81 | 7.82 ± 0.85 | 7.63 ± 0.70 | 7.65 ± 0.73 | 0.6110 |
| PCT | 0.23 ± 0.08 | 0.20 ± 0.06 | 0.30 ± 0.14 | 0.29 ± 0.08 | 0.35± 0.11 | <0.001 * |
| PDW | 12.63 ± 2.42 | 11.74 ± 3.36 | 11.62 ± 1.42 | 12.91 ± 2.03 | 12.09 ± 2.19 | 0.2710 |
Values are expressed as mean ± standard deviation (SD). Hb, haemoglobin; HCT, Haematocrit; RBC, red blood cell count; MCV, mean cell volume; MCH, mean cell haemoglobin; MCHC, mean cell haemoglobin concentration; RDW, Red cell distribution width; MPV, mean platelet volume; PLT, platelets count; PCT, plateletcrit; PDW, platelets distribution width; WBC, white blood cells. * significant at p ≤ 0.05.