Figure 3.

Effects of gukulenin A on cell-cycle regulation in human ovarian cancer cells. A2780 cells were treated with the indicated concentration of gukulenin A (15, 30, and 60 nM) for 24 and 48 h, and then stained with propidium iodide (PI). (A) Flow cytometry analysis was performed for the cell-cycle distribution profiles of the cells. (B) The percentages of cells in the sub G1, G0/G1, S, and G2/M phases of the cell cycle were shown as a graph. The data are representative of three independent experiments.