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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2018 Feb 15;27(4):398–404. doi: 10.1002/pds.4398

Table 2.

Positive predictive values (PPVs)* associated with inpatient administrative diagnosis codes for acute myocardial infarction (AMI) by position.

PPVs for all potential AMI cases (N = 89) PPVs for principal position AMI diagnoses (N = 30) PPVs for secondary AMI diagnoses (N = 33) PPVs for position-unspecified** AMI diagnoses (N = 26)
All AMI codes 75% (67/89, 95% CI: 65–84%) 93% (28/30, 95% CI: 78–99%) 88% (29/33, 95% CI: 72–97%) 38% (10/26, 95% CI: 20–59%)
By diagnosis code recorded in administrative data
410.x0 33% (5/15, 95% CI: 12–62%) 100% (1/1, 95% CI: 3–100%) 33% (1/3, 95% CI: 1–91%) 27% (3/11, 95% CI: 6–61%)
410.x1 84% (62/74, 95% CI: 73–91%) 93% (27/29, 95% CI: 77–99%) 93% (28/30, 95% CI: 78–99%) 47% (7/15, 95% CI: 21–73%)
Data Partner type
Insurer/claims-based 71% (49/69, 95% CI: 59–81%) 92% (22/24, 95% CI: 73–99%) 89% (17/19, 95% CI: 67–99%) 38% (10/26, 95% CI: 20–59%)
Integrated care delivery systems 90% (18/20, 95% CI: 68–99%) 100% (6/6, 95% CI: 54–100%) 86% (12/14, 95% CI: 57–98%) --
By whether an AMI code was observed in prior 183 days
No prior AMI 78% (54/69, 95% CI: 67–87%) 92% (23/25, 95% CI: 74–99%) 96% (22/23, 95% CI: 78–100%) 43% (9/21, 95% CI: 22–66%)
Prior AMI 65% (13/20, 95% CI: 41–85%) 100% (5/5, 95% CI: 48–100%) 70% (7/10, 95% CI: 35–93%) 20% (1/5, 95% CI: 1–72%)
*

Statistics reported in this table reflect the PPV of administrative ICD-9-CM AMI diagnosis codes for a confirmed (definite, probable, or possible) acute AMI. Patients with a classification of insufficient information / acute TEE status unknown were removed from the denominator for the PPV calculations and not included in this table.

**

Within the Sentinel Distributed Database, a position-unspecified inpatient diagnosis is a non-facility professional/provider claim associated with an inpatient encounter.