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. Author manuscript; available in PMC: 2019 Mar 11.
Published in final edited form as: Mol Psychiatry. 2018 Aug 14:10.1038/s41380-018-0119-0. doi: 10.1038/s41380-018-0119-0

Figure 5. Data demonstrating clinical effects of the mGluR2 PAM JNJ-40411813 on panic symptoms.

Figure 5.

The changes in Panic Disorder Severity Scale (PDSS) show that all five subjects exhibited remission of their panic symptoms following 2 – 4 weeks of mGluR2 PAM therapy. NOTE: PDSS range = 0 – 28, Scores ≥ 8 consistent with DSM-IV Panic Disorder81.