Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A. DNA sequence of the 25mer PIK3CA substrate with the two target cytosines denoted. B. Deamination by the recombinant APOBEC3B of the PIK3CA target substrate. Over the course of four hours, accumulation of P1 and P2 corresponding to the central and 5’ cytosine deamination event was observed, denoted on the timecourse.
