Table 3.
Comparison of metabolism indexes between patients on olanzapine and other SGAs 1 with analysis of variance of repeated measures.
| Variables | Admission | Discharge | Time effect | Group effect | Time×Group | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Olanzapine (n=62) |
Other SGAs1 (n=86) |
Olanzapine (n=62) |
Other SGAs1 (n=86) |
F | p | F | p | F | p | |
| TC (mmol/L) | 4.33(0.92) | 4.21(0.91) | 4.87(1.11) | 4.30(0.99) | 11.07 | 0.001 | 7.20 | 0.008 | 5.66 | 0.019 |
| TG (mmol/L) | 1.18(1.05) | 1.27(0.70) | 2.60(1.63) | 1.74 (0.94) | 69.02 | <0.001 | 8.41 | 0.004 | 17.32 | <0.001 |
| HDL (mmol/L) | 1.53(0.28) | 1.47(0.31) | 1.40(0.26) | 1.42 (0.34) | 12.63 | 0.001 | 0.16 | 0.688 | 2.12 | 0.147 |
| LDL (mmol/L) | 2.94(0.87) | 2.89(0.80) | 3.10(0.84) | 2.88 (0.82) | 0.93 | 0.336 | 1.33 | 0.25 | 1.18 | 0.278 |
| GLU (mmol/L) | 4.75(1.15) | 4.70(0.71) | 5.14(1.04) | 5.01(1.17) | 11.91 | 0.001 | 0.49 | 0.485 | 0.16 | 0.686 |
| GSP (mmol/L) | 1.71(0.22) | 1.679(0.23) | 1.84(0.38) | 3.68 (17.28) | 0.95 | 0.331 | 0.67 | 0.414 | 0.73 | 0.394 |
| β-OHB (mmol/L) | 0.10(0.13) | 0.08(0.05) | 0.17(0.20) | 0.15(0.20) | 16.90 | <0.001 | 1.71 | 0.301 | 0.02 | 0.893 |
| Body weight (kg) | 60.4(9.5) | 62.1(13.6) | 64.4(8.4) | 63.1(12.9) | 126.60 | <0.001 | 0.01 | 0.972 | 20.71 | <0.001 |
1See Table 1
Abbreviations: TC: Total Cholesterol; TG: Triglycerides; HDL: High Density Lipoprotein Cholesterol; LDL: Low Density Lipoprotein Cholesterol; GLU: Glucose; GSP: glycosylated serum protein; β-OHB: Beta-hydroxybutyric Acid.