Table 3.
Associations between obesity during childhood, adolescence and adulthood and cardio metabolic outcomes in the 82 Pelotas cohort
| SBP (mmHg) | DBP (mmHg) | Random glucose (mg/dl) | HDL Cholesterol (mg/dl) | LDL cholesterol (mg/dl) | Triglycerides (mg / dl) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Mean (95%CI) | β* (95%CI) | Mean (95%CI) | β* (95%CI) | Mean (95%CI) | β** (95%CI) | Mean (95%CI) | β** (95%CI) | Mean (95%CI) | β** (95%CI) | Mean (95%CI) | β** (95%CI) | |
| 2853 | |||||||||||||
| Obesity pattern | |||||||||||||
| Never | 2036 | 121.6 (121.0;122.3) | Reference | 74.1 (73.7;74.6) | Reference | 87.6 (86.7;88.6) | Reference | 57.5 (58.9;58.2) | Reference | 108.4 (107.0;109.9) | Reference | 115.9 (111.8;120.0) | Reference |
| Chilhood or adolescence onlya | 253 | 122.4 (120.6;124.2) | −0.5 (− 2.2;1.3) | 74.2 (72.9;75.5) | − 0.2 (− 1.6;1.1) | 88.3 (85.6;90.1) | 0.1 (− 3.6;3.9) | 57.0 (55.1;58.9) | −0.3 (− 2.2; 1.6) | 108.8 (104.7;113.0) | − 0.3 (− 4.74.1) | 112.9 (99.0;126.9) | 1.0 (0.9;1.1) |
| Adulthood onlyb | 343 | 129.8 (128.3;131.2) |
8.4 (7.0;9.8) |
81.5 (80.5;82.5) |
7.4 (6.4;8.5) |
94.6 (91.2;98.1) |
7.2 (4.2;10.1) |
53.1 (51.8;54.4) |
−4.5 (−6.0;-3.0) |
117.9 (114.8;121.0) |
9.4 (5.9;12.8) |
169.1 (148.6;189.6) |
1.4 (1.3;1.5) |
| Childhood + adulthood | 85 | 127.0 (124.7;1291.3) |
4.6 (1.9;7.3) |
79.8 (78.1;81.5) |
5.5 (3.5;7.5) |
88.8 (85.6;92.0) |
0.6 (−5.1;6.3) |
52.4 (50.0;54.8) |
−4.8 (−7.7;-2.0) |
119.3 (112.4;126.1) |
10.1 (3.4;16.8) |
156.5 133.2;179.8 |
1.3 (1.2;1.5) |
| Adolescence + adulthood | 85 | 134.3 (130.2;138.3) |
13.3 (10.6;16.0) |
83.8 (81.4;86.2) |
9.9 (7.8;11.9) |
114.5 (101.0;128.0) |
27.2 (21.4;32.9) |
52.5 (49.6;55.4) |
−5.6 (−8.5;-2.7) |
118.3 (110.9;125.8) |
9.7 (2.9;16.5) |
172.8 (142.7;202.9) |
1.5 (1.3;1.7) |
| Always | 51 | 137.9 (131.6;144.2) |
14.8 (10.6;18.0) |
85.4 (81.8;89.0) |
10.9 (8.1;13.7) |
108.0 (87.9;128.1) |
19.2 (11.4;26.9) |
51.5 (47.1;55.9) |
−5.4 (−9.4;-1.5) |
112.2 (102.8;121.7) |
1.9 (−7.2;11.1) |
184.4 (132.5;236.3) |
1.4 (1.2;1.6) |
*Adjusted for sex, birth weight, skin color, family income at birth, maternal schooling and maternal smoking during pregnancy
**Adjusted for sex, birth weight, skin color, family income at birth, maternal schooling, maternal smoking during pregnancy and fasting time
aOverweight/ obesity (BMI/age) WHO charts, 2006
bAdults only: overweight BMI ≥25; obesity BMI ≥ 30