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. 2019 Mar 11;16:59. doi: 10.1186/s12974-019-1440-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Intrathecal immune activity in patients who develop multiple sclerosis. Cerebrospinal fluid levels of TNF-α, IL-10, IL-17A, and CXCL13 in patients who develop multiple sclerosis (MS-ON) and their correlation with a albumin ratio, b leukocyte count, and c IgG index. Open circles indicate patients that were diagnosed with MS 3 to 12 months after ON onset