Figure 1.

Experimental timeline. LAD, left anterior descending coronary artery; PBS, phosphate‐buffered saline; MAP, mean arterial pressure; SvO₂, mixed venous oxygen saturation; HR, heart rate; MPAP, mean pulmonary arterial pressure; EDV, end‐diastolic volume; ESV, end‐systolic volume; LVEF, left ventricular ejection fraction; dP/dtmax, pressure development during isovolumic contraction; dP/dtmin, pressure development during isovolumic relaxation; VCO, vena cava occlusion; ESPVR and EDPVR, end‐systolic and end‐diastolic pressure volume relationship; Emax, maximal ventricular elastance; PRSW, preload recruitable stroke work; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CK, creatine phosphokinase.