Table 3. UVC-Induced Damage Susceptibility and Number of Bipyrimidine Sites of N-Ras Oligonucleotidesa.
| sequence number | damage susceptibility | TT | CC | CT |
|---|---|---|---|---|
| S37-43 | 0.69 ± 0.02 | 6 | 1 | 4 |
| S151-157 | 0.53 ± 0.03 | 6 | 1 | 3 |
| S169-175 | 0.33 ± 0.02 | 6 | 0 | 5 |
| S139-145 | 0.69 ± 0.01 | 5 | 2 | 4 |
| S115-121 | 0.32 ± 0.01 | 5 | 2 | 3 |
| S85-91 | 0.26 ± 0.02 | 5 | 0 | 3 |
| S127-133 | 0.19 ± 0.00 | 5 | 2 | 3 |
| S49-55 | 0.18 ± 0.02 | 5 | 2 | 3 |
| S13-19 | 0.31 ± 0.01 | 4 | 3 | 1 |
| S25-31 | 0.23 ± 0.03 | 4 | 1 | 5 |
| S103-109 | 0.45 ± 0.02 | 3 | 1 | 5 |
| S133-139 | 0.30 ± 0.02 | 3 | 4 | 4 |
| S163-169 | 0.26 ± 0.01 | 3 | 2 | 3 |
| S157-163 | 0.23 ± 0.02 | 3 | 1 | 5 |
| S121-127 | 0.22 ± 0.01 | 3 | 2 | 4 |
| S43-49 | 0.21 ± 0.01 | 3 | 2 | 3 |
| S79-85 | 0.16 ± 0.03 | 3 | 1 | 2 |
| S97-103 | 0.41 ± 0.02 | 2 | 2 | 6 |
| S91-97 | 0.26 ± 0.00 | 2 | 3 | 4 |
| S19-25 | 0.19 ± 0.01 | 2 | 2 | 7 |
| S73-79 | 0.18 ± 0.03 | 2 | 4 | 8 |
| S184-190 | 0.13 ± 0.01 | 2 | 2 | 0 |
| S61-67 | 0.09 ± 0.01 | 2 | 1 | 5 |
| S1-7 | 0.12 ± 0.03 | 2 | 1 | 4 |
| S175-181 | 0.34 ± 0.02 | 1 | 4 | 6 |
| S55-61 | 0.10 ± 0.03 | 1 | 2 | 5 |
| S31-37 | 0.01 ± 0.02 | 1 | 3 | 5 |
| S7-13 | 0.00 ± 0.02 | 1 | 5 | 2 |
| S67-73 | 0.00 ± 0.03 | 1 | 2 | 8 |
| S145-151 | 0.00 ± 0.02 | 1 | 4 | 5 |
| S181-187 | 0.00 ± 0.02 | 1 | 3 | 1 |
| S109-115 | 0.00 ± 0.03 | 0 | 4 | 4 |
a
This table is ordered by the number of TT bipyrimidine sites in the N-Ras oligonucleotides used in this study. The damage susceptibility is calculated as (1 – F), where F = Fi/Fc, Fi is the fluorescence intensity of EG-dsDNA upon damage and Fc is the fluorescence intensity of the undamaged DNA-EG control sample. The columns headed as TT, CC, and CT list the number of respective bipyrimidine sites in the oligonucleotides.