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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Alcohol Clin Exp Res. 2019 Feb 12;43(3):439–452. doi: 10.1111/acer.13947

Figure 6. Quantitative trait loci (QTLs) map using the EtOH-Adj data in the forebrain and brainstem.

Figure 6.

(A) Interval genome-wide mapping of the forebrain showed no suggestive or significant QTLs (Record ID: 18128). (B) Interval genome-wide mapping of the brainstem (Record ID: 18126) showed (C) a significant QTL (LRS = 14.3) on Chr4 between 95–103 Mb and (D) a significant QTL on Chr14 between 45–47.5 Mb (LRS = 16.5). For all, the x-axis denotes chromosome and megabases (Mb) with yellow dashes representing the location of SNPs and the y-axis denotes the LRS-value. The blue line represents the LRS scores of this trait. Red and green lines represent additive effects of the B6 and D2 alleles, respectively. The horizontal lines for C and D indicate genome-wide suggestive (bottom, gray line, LRS = 8.83) and significant (top, pink line, LRS = 14.21) thresholds. Green, navy, purple, red, and yellow bars in the section above the blue line represent genes.