Table 2.

TAP amber and red flag regions, as defined by the entire set of 242 CSTs

Metric	Amber flag region	Red flag region
Total CDR length	54 $\le$ L $\le$ 60	L $>$ 60
PSH, CDR vicinity	83.84 $\le$ PSH $\le$ 100.71	PSH $<$ 83.84
	156.20 $\le$ PSH $\le$ 173.85	PSH $>$ 173.85
PPC, CDR vicinity	1.25 $\le$ PPC $\le$ 3.16	PPC $>$ 3.16
PNC, CDR vicinity	1.84 $\le$ PNC $\le$ 3.50	PNC $>$ 3.50
SFvCSP	-20.40 $\le$ SFvCSP $\le$ -6.30	SFvCSP $<$ -20.40

PSH score is calculated with the Kyte and Doolittle (31) hydrophobicity scale. L, length.