TABLE 2.
Coordinates of functional ROIs for the food-evaluation functional MRI task1
| L/R | ROI | Voxels | Z 2 | x | y | z |
| R | Orbitofrontal cortex | 89 | 3.38 | 22 | 32 | −22 |
| L | Orbitofrontal cortex | 86 | 3.70 | −26 | 34 | −18 |
| R | Hippocampus | 184 | 3.72 | 30 | −30 | −8 |
| L | Hippocampus | 152 | 4.04 | −22 | −30 | −6 |
| R | Nucleus accumbens | 45 | 3.36 | 10 | 16 | −4 |
| L | Nucleus accumbens | 175 | 4.37 | −8 | 10 | −8 |
| R | Caudate | 32 | 3.36 | 10 | 16 | −4 |
| L | Caudate | 134 | 4.11 | −12 | 12 | −6 |
| R | Anterior insula | 463 | 5.24 | 36 | 8 | −16 |
| L | Anterior insula | 204 | 4.93 | −38 | 6 | −12 |
| R | Amygdala | 64 | 3.65 | 22 | −2 | −16 |
| L | Amygdala | 20 | 3.05 | −20 | 2 | −20 |
Activation within functional ROIs at the second level group mixed-effects analysis for FOOD minus object picture contrast at the Fasted-Initial visit (n = 21). Results represent the L or R hemisphere, number of voxels within a cluster (2 mm3; minimum cluster size: 10), Z statistic using a statistical threshold voxel-wise FDR P < 0.05, and coordinates of peak statistical voxel (x, y, z in Montreal Neurological Institute 152 space) in each ROI. Fasted-Initial, first scanning visit with 16-h overnight fast and given subcutaneous saline injection; FDR, false discovery rate; FOOD, high- or low-energy foods; L, left hemisphere; R, right hemisphere; ROI, region of interest.
2All FDRs, P < 0.05.