Table II.

Genotype and variant allele frequencies for FTO gene polymorphism rs8050136: A>C.

Polymorphism	Genotype	T2D patients	Mutated allele frequency	Prediabetic patients	Mutated allele frequency	Healthy controls	Mutated allele frequency	p
rs8050136	AA	130 (24.7%)	0.50	17 (41.3%)	0.46	84 (26.0%)	0.51	p preD/ctrl = 0.100
	AC	264 (50.1%)		16 (30.4%)		150 (46.4%)		p T2D/preD = 0.576
	CC	133 (25.2%)		13 (28.3%)		89 (27.6%)		P preD/ctrl = 0.224
	Total	527	P1 =0.999	46	P2=0.127	323	P3=0.443	p=0.258

p – significance of the 2 test for comparison of genotype frequencies between T2D, prediabetic patients and healthy controls ppreD/ctrl – significance of the 2 test for comparison of genotype frequencies between T2D and prediabetic patients p significance of the 2 test for comparison of genotype frequencies between T2D patients and healthy controls p T2D/preD – significance of the 2 test for comparison of genotype frequencies between prediabetic patients and healthy controls

P¹ – value for Hardy-Weinberg equilibrium for T2D patients group

P² – value for Hardy-Weinberg equilibrium for pre-diabetic patients group

P³ – value for Hardy-Weinberg equilibrium for healthy controls group