Table I.

Baseline biochemical parameters at the enrolment of the study.

	x±SD Median (25 – 75 IQ)	Reference values
Calcium, number (%):	2.2 (2.07 – 2.3)	2.15–2.65 mmol/L
< 2.15, mmol/L	20 (35.7%)
>2.65, mmol/L	2 (3.5%)
Phosphate, number (%):	1.7±0.4	0.8–1.55 mmol/L
>1.55 ( >2.0), mmol/L	33–58.9% (16 = 28.5%)
Alkaline phosphatase, U/L	70 (52 – 96.2)	40–120 U/L
iPTH, pg/mL	115.5 (38 – 341.8)
number (%):	33 (58.9%)
<150	9 (16.0%)
>600
1,25 dihydroxyvitamin D, ng/mL	36.7±19.1	7.6–147.8 ng/mL
number (%):
<20	10 (17.8%)
20–30	15 (26.7%)
>30	31 (55.3%)
FGF 23, pg/mL	812 (333–1500)	3.12–200 pg/mL
number (%):
< 200	7
>200	49 (87.5%)
>1000*	25 (44.6%)
Klotho, ng/mL	0.039 (0.028–0.066)	0.156–10 ng/mL
number (%):
25% Percentiles	19 (33.9%)
M	21(37.5%)
75% Percentiles	16 (28.6%)
Treatment: yes
Vitamin D	23 (41%)
Phosphate binders
Calcium based	42 (75%)
Non calcium based	3 (5.3%)
ESA	33 (58.9%)
Anti hypertensive drugs	33 (58.9%)

ESA= erythropoietin stimulating agents

^*out of patients with FGF23 > 200 pg/mL