Table 3.
Parameters | Disease-free survival (p value) | Overall survival (p value) |
---|---|---|
Clinical parameters | ||
Age | 0.338 | 0.556 |
Tumour location | 0.396 | 0.752 |
Stage | 1.000 | 0.198 |
Pre-treatment values of functional parameters and tumour volume | ||
ADC (x 10-3 mm2/s) | 0.856 | 0.012* |
Ktrans (min-1) | 0.116 | 0.026* |
Ve | 0.754 | 0.293 |
Vp | 0.165 | 0.342 |
Tumour volume | 0.959 | 0.048* |
Relative changes after 10 Gy of functional parameters and tumour volume | ||
ΔADC (%) | 0.740 | 0.061 |
ΔKtrans | 0.688 | 0.014* |
ΔVe | 0.957 | 0.405 |
ΔVp | 0.672 | 0.077 |
ΔTumour volume (ml) | 0.495 | 0.486 |
= significant predictor at univariate analysis; ADC = Apparent diffusion coefficient; Ktrans = volume transfer constant; Ve = extracellular extravascular volume fraction; Vp = plasma volume fraction; Δ = relative change in the parameter