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DDRs contribution in cancer hallmarks. Representative circular diagram of the hallmarks of cancer, adapted from Hanahan and Weinberg, 2011. In the center, a representative confocal image of a melanoma cancer cell (A375) seeded into collagen fibers (grey) and expressing DDR1 (red). The nucleus is in blue. The difference in the front size is related to the reported involvement of one of hte DDR more than the other in the literature.
