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. Author manuscript; available in PMC: 2019 Mar 11.
Published in final edited form as: J Allergy Clin Immunol. 2018 Nov 22;143(3):1258–1261. doi: 10.1016/j.jaci.2018.11.011

Fig. 1.

Fig. 1

Scheme, time course of study, and development of specific IgG responses. A, The study was conducted over a period of 2 years (x-axis: weeks). The 13 study visits are indicated as well as the time points of vaccination (I-IV), blood sampling, and skin testing. Development of specific IgG responses (y-axes: OD increases compared with baseline) against, Bet v 1 (B), F1 (C), F2 (D) birch pollen–specific IgE (E) (y-axis: kUA/L), and birch pollen–induced wheal reactions (F) (y-axis: mm2) during the 2 years of the study (x-axes: wk/visits) in the active group (grey) and the placebo group (black). Time points of vaccination and pollen seasons (boxed) are indicated. SPT, Skin prick test.