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. 2019 Feb 27;15(2):e1007599. doi: 10.1371/journal.ppat.1007599

Fig 3. Systemic inflammation does not accelerate pRBC clearance by Py17XNL-specific antibodies.

Fig 3

(A) Serum cytokine levels in mice (n = 5/group) receiving Py17XNL-immune serum and TLR4 (LPS) or TLR9 (CpG) agonists, measured at 7 hours after infection with CTFR+ pRBC. Each dot represents an individual mouse; DL = detection limit of assay. (B) Loss of Gen0 (CTFR+) pRBC over the first 25 hours, and emergence over 3 days of Gen1+ (CTFR-) pRBC in mice (n = 5/group) receiving Py17XNL-immune or non-immune serum, and stimulated via TLR4 or TLR9, or with control saline. Data representative of two independent experiments showing similar results.