Table 2.

Propensity-Score Matched Analyses Comparing Outcomes Between Nitrofurantoin and Other Antibiotics

Outcomes	Cefalexin (n = 7200) Versus Nitrofurantoin (n = 21 600)		Ciprofloxacin (n = 3717) Versus Nitrofurantoin (n = 11 151)		Co-amoxiclav (n = 5262) Versus Nitrofurantoin (n = 15 786)
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
Reconsultation and represcription within 14 days	0.85 (0.75–0.98)	.020	0.48 (0.38–0.61)	<.001	0.77 (0.64–0.93)	.006
Hospitalized for UTI within 14 days	0.96 (0.78–1.18)	.673	0.84 (0.57–1.26)	.408	0.94 (0.68–1.31)	.731
Hospitalized for sepsis within 14 days	1.89 (1.03–3.47)	.038	3.21 (1.59–6.50)	.001	1.91 (0.98–3.73)	.058
Hospitalized for AKI within 14 days	0.55 (0.23–1.31)	.175	1.53 (0.49–4.79)	.457	0.87 (0.40–1.90)	.727
Death within 28 days	1.44 (1.12–1.85)	.004	1.18 (0.83–1.68)	.353	1.39 (0.93–2.07)	.108

Abbreviations: AKI, acute kidney injury; CI, confidence interval; OR, odds ratio; UTI, urinary tract infection.