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. 2019 Feb 18;54(4):1195–1208. doi: 10.3892/ijo.2019.4717

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Copyright: © An et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of COPB2 gene knockdown on apoptosis, as determined by fluorescence-activated cell sorting detection. (A) Images of Lv-shCOPB2 and Lv-shCtrl groups demonstrating the level of apoptosis in BGC-823 cells following infection. (B) A total of 5 days post-infection, the percentage of apoptosis in BGC-823 cells from the Lv-shCOPB2 group was significantly increased compared with in the Lv-shCtrl group (P<0.001), thus suggesting that the COPB2 gene may be associated with apoptosis of BGC-823 cells. ^***P<0.01, compared with the Lv-shCtrl group. COPB2, coatomer protein complex subunit β2; Lv, lentivirus; sh, short hairpin RNA.