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. 2019 Feb 22;54(4):1168–1182. doi: 10.3892/ijo.2019.4723

Table I.

Median patient age at first tumor onset.

p53 mutation No. patients Median age, years P-value Q
NULL 519 30.0 - -
MIS 1276 30.0 0.3801 0.3801
R248Q 45 23.0a 0.0171 0.0855
R248W 69 24.0 0.0915 0.1525
R175H 73 26.0 0.2468 0.3085
R273H 54 27.5 0.0717 0.1525
a

P<0.05 and Q<0.1 vs. NULL group. p53, tumor suppressor p53; MIS, any missense mutation.