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. 2019 Feb 22;54(4):1168–1182. doi: 10.3892/ijo.2019.4723

Table IV.

Distribution of primary tumor types in patients with germline TP53 mutations.

p53 mutation Sarcoma, n Carcinoma, n Other, n P-value Q
NULL 190 97 479 - -
MISa 364 380 1266 <0.0001 0.0005
R248Q 21 7 55 0.5308 0.6635
R248Wa 16 19 77 0.0374 0.0623
R175H 27 14 77 0.8494 0.8494
R273Ha 29 17 41 0.0181 0.0453
a

P<0.05 and Q<0.1 vs. NULL group for primary tumor type. p53, tumor suppressor p53; MIS, any missense mutation.