Table I.
List of compounds.
| Common name, synonym | Chemical, formal name | Laboratory number | IC50 (mM) | Source |
|---|---|---|---|---|
| Salicylic acid, SA | 2-hydroxybenzoic acid | Not applicable | 2.6 | Commercially available |
| Aspirin, ortho-aspirin | 2-acetoxybenzoic acid, acetylsalicylic acid | PN502 | 1.8 | Commercially available |
| Diaspirin, DiA | Bis-carboxyphenylsuccinate | PN508 | 0.8 | (27) |
| Fumaryldiaspirin, F-DiA | Bis-carboxyphenylfumarate | PN517 | 0.2 | (27) |
| Not applicable | m-bromobenzoylsalicylic acid | PN524 | 0.4 | (27) |
| Not applicable | Isopropyl m-bromobenzoylsalicylate | PN529 | ND | (27) |
| meta-aspirin | 3-acetoxybenzoic acid | PN548 | 3.8 | Synthesised in this study |
| para-aspirin | 4-acetoxybenzoic acid | PN549 | 4.9 | Synthesised in this study |
| Thioaspirin, ortho-TASP | 2-acetylthiobenzoic acid | PN590 | 0.2 | Synthesised in this study |
| m-thioaspirin, meta-TASP | 3-acetylthiobenzoic acid | PN591 | 0.5 | Synthesised in this study |
| p-thioaspirin, para-TASP | 4-acetylthiobenzoic acid | PN592 | 0.8 | Synthesised in this study |
| Diflunisal, DIF | 5-(2,4-difluorophenyl) salicylic acid | Not applicable | 0.08 | Commercially available |
IC50, half maximal inhibitory concentration; ND, not determined.