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. Author manuscript; available in PMC: 2019 Jul 21.
Published in final edited form as: Nature. 2019 Jan 21;566(7744):393–397. doi: 10.1038/s41586-019-0879-y

Extended Data Figure 7. Relative light chain diversity estimation.

Extended Data Figure 7.

Using previously reported datasets of paired heavy and light antibody chains, clonotype diversity was estimated for heavy and light chains using both Chao2 and Recon estimators. Estimates are shown in filled or unfilled points. Lines indicate the least squares polynomial best fit (degree=2) and is extrapolated to include both the lowest (1.17×108) and highest (9.06×108) number of UMI-corrected sequences from the 10 sequenced subjects.