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Agarose gel electrophoresis showing the dose response of compounds A) 1, B) 2, C) 3 and D) 4 incubated with 40 μg/mL pUC19 DNA with irradiation (470 nm light). Lanes 1 and 12, DNA ladder; lane 2, EcoRI; lane 3, Cu(OP)2; lane 4−11, 0−500 μM. EcoRI and Cu(OP)2 are controls for linear and relaxed circle DNA. See SI for full gels.
