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Cancer-associated fibroblasts enhance the clonogenic growth potential of PDAC. A, Colony formation by PDAC cell lines (Capan-1, and BxPC-3) and B, a PDX (JH102) cells following co-culture with CAFs or nHLFs for 7 days. Data represent the mean and SD of 4 experiments. *P < 0.05, **P < 0.005. C, Primary and secondary colony formation by Capan-1 cells cultured with or without CAFs for seven days. Data represent the mean and SD of 4 experiments. *P < 0.05.
