Fig. 4.
Group hippocampal shape differences between HT (e3/e4, N = 36) /HM (e4/e4, N = 37) and NC (e3/e3, N = 44) on the cognitively unimpaired cohort, at the nominal 0.05 level, uncorrected. (A) Between NC and HE, the overall significances after multiple comparisons with permutation test were PLH = 0.0296 and PRH = 0.3579. (B) Between NC and HM, the overall significances after multiple comparisons with permutation test were PLH = 0.0105 and PRH = 0.1886. LH: left hippocampus; RH: right hippocampus; HT: heterozygotes; HM: homozygotes; NC: no-carriers.