Table 1.
The genotype and the allele frequencies of ESR1 polymorphisms in patients and controls.
| Polymorphism | Radiographic knee OA (%) | Control (%) | OR (95% CI) | P-value |
|---|---|---|---|---|
| rs2234693 | ||||
| Genotypes | ||||
| TT | 30(33.3) | 24(26.7) | Ref. | |
| TC | 42(46.7) | 37(41.1) | 1.253(0.695–2.260) | 0.453 |
| CC | 18(20.0) | 29(32.2) | 0.526(0.266–1.038) | 0.064 |
| Allele | ||||
| T | 102(53.7) | 85(44.7) | 1.462(0.965–2.214) | 0.073 |
| C | 78(46.3) | 95(55.3) | 0.684(0.452–1.037) | 0.073 |
| rs9340799 | ||||
| Genotypes | ||||
| AA | 51(56.7) | 45(50.0) | Ref. | |
| AG | 28(31.1) | 32(35.6) | 0.819(0.440–1.523) | 0.527 |
| GG | 11(12.2) | 13(14.4) | 0.825(0.348–1.953) | 0.661 |
| Allele | ||||
| A | 130(72.2) | 122(67.8) | 1.236(0.787–1.942) | 0.358 |
| G | 50(27.8) | 58(32.2) | 0.809(0.515–1.271) | 0.358 |
OR: Odds Ratio; CI: Confidence Interval.